| Prof YUNG Shu-hang, Patrick, MH, JP |
| Dr WONG Ronald Man Yeung |
| Dr ONG Tim-yun, Michael |
| Dr LING Ka-kin, Samuel |
| Dr LAU Yiu-chung, Adam |
| Dr LAW Sheung-wai |
| Dr WONG Wing-yee, Clara |
| Dr HO Ki-wai, Kevin |
| Dr LAM Tsz-ping |
| Dr Kwan Cheuk-kin, Eric |
| Prof LEUNG Ping-chung, SBS, OBE, JP |
| Prof CHAN Kai-ming, OBE, JP |
| Prof LEUNG Kwok-sui |
| Prof CHENG Chun-yiu, Jack |
| Prof KUMTA Shekhar Madhukar |
| Prof QIN Ling |
| Prof WANG Huating |
| Prof CHEUNG Wing-hoi, Louis |
| Prof LUI Po-yee, Pauline |
| Prof LEE Yuk-wai, Wayne |
| Prof XU Jiankun, Jerry |
| Prof ZHANG Ning |
| Dr LIN Sien |
| Dr CHUI Chun-sing, Elvis |
| Dr TONG Wenxue |
| Dr CHEN Xiaona |
| Dr HSUEH Yu-sheng, Delon |
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CONTACT INFORMATION
Office : (852) 3763-6111
Email : twxleo@cuhk.edu.hk
ACADEMIC ENGAGEMENT
Postgraduate teaching:
MPhil/PhD in Orthopaedics & Traumatology
ORCID: 0000-0003-3462-2740
ResearcherID: DYF-2624-2022 |
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Dr. TONG Wenxue 童文學 |
BSc (SDNU), Master of Cell Biology (SJTU), PhD (CUHK)
Research Assistant Professor
研究助理教授
BIOGRAPHY
Dr. Tong obtained his BSc degree from the College of Life Sciences, Shandong Normal University (SDNU) in 2009. He continued his study in Shanghai Jiao Tong University (SJTU) School of Medicine to research the role of articular cartilage stem cells in osteoarthritis, and obtained his Master's degree in cell biology in 2012. He graduated from the Department of Orthopaedics and Traumatology in 2017 by investigating the role of Wnt16 in skeletal development and osteoarthritis pathology and continued the postdoctoral training in the Department of Orthopaedics and Traumatology of CUHK.
Dr. Tong focused on gene function, gene therapy, and biodegradable materials, especially Mg-based implant studies. Dr. Tong has achieved many academic accomplishments, including a total of 26 publications with an H-Index 13, with a research article as the first author from his Ph.D. thesis published in Annals of the Rheumatic Diseases (IF=27.973). Dr. Tong has recently obtained a Health and Medical Research Fund (HMRF) as a PI and Impact Postdoctoral Fellow Scheme (IPDFS), and two Direct Grants as Co-PI. Dr. Tong also serves as a core member or coordinator to assist in drafting several research grants, such as the Theme-based Research Scheme (TRS), Areas of Excellence Scheme (AoE), and CUHK Hong Kong-Shenzhen Innovation and Technology Research Institute (Futian, FITRI) Platform Scheme, NSFC-RGC, MHKJFS (ITF), etc. Dr. Tong also established a start-up company, Targene Biotech (Hong Kong) Limited, as the Chief Executive Officer (CEO) in 2019 to push forward the gene therapy research translation and obtained the support of the Technology Start-up Support Scheme for Universities (TSSSU).
EXPERTISE
- Osteoarthritis Pathology and Cartilage Regeneration
- Gene Therapy
- Mg-based Biomaterial R&D and Translational Research
SPECIALISED RESEARCH AREAS
- Gene Function in Musculoskeletal Development and Disease Pathology
- Gene Therapy Using Tissue Targeting Adeno-associated Virus
- Biomaterial R&D and Translation
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SELECTED PUBLICATION
| 1. |
Yao Z#, Yuan W#, Xu J, Tong W, Mi J, Ho PC, Chow DHK, Li Y, Yao H, Li X, Xu S, Guo J, Zhu Q, Bian L*, Qin L*. Magnesium-Encapsulated Injectable Hydrogel and 3D-Engineered Polycaprolactone Conduit Facilitate Peripheral Nerve Regeneration. Advanced Science, 2022 Jul;9(21):e2202102. (IF=17.521) |
| 2. |
Xu H#, Zhu Y#, Xu J, Tong W, Hu S, Yao H, Li J, Lee C*, Chan H*. Injectable bioactive glass/sodium alginate hydrogel with immunomodulatory and angiogenic properties for enhanced tendon healing. Bioeng Transl Med, May 2022. (IF=10.684) |
| 3. |
Dai B#, Li X#, Xu J*, Zhu Y, Huang L, Tong W, Yao H, Chow DH, Qin L*. Synergistic effects of magnesium ions and simvastatin on attenuation of high-fat diet-induced bone loss. Bioactive Materials. 2021 Feb 3;6(8):2511-2522. (IF=16.874) |
| 4. |
Tong W#, Zeng Y#, Chow D, Yeung W, Xu J, Deng Y, Ho K, Qin L*, Mak K*. Wnt16 attenuates osteoarthritis progression through a PCP/JNK-mTORC1-PTHrP cascade. Annals of the Rheumatic Diseases. 2019 Feb 11. (IF=27.973) |
| 5. |
Deng Y, Lu J, Li W, Wu A, Zhang X, Tong W, Ho K, Qin L, Song H*, Mak K*. Reciprocal inhibition of YAP/TAZ and NF-κB regulates osteoarthritic cartilage degradation. Nature Communications. 2018 Nov 1;9(1):4564. (IF=17.694) |
| 6. |
Tong W, Mak K, Qin L*. Introducing Wnt16 attenuates the severity of osteoarthritis. Journal of Orthopaedic Translation. Volume 7, October 2016, P126. (IF=4.52) |
| 7. |
Wang#, Wang C#, Zhang N, Tong W, Zhang X, Li Q*. Mechanical stimulation orchestrates the osteogenic differentiation of human bone marrow stromal cells by regulating HDAC1. Cell Death & Disease. 2016 (IF=9.685) |
| 8. |
Tong W, Geng Y, Huang Y, Shi Y, Xiang S, Zhang N, Qin L, Shi Q, Chen Q, Dai K, Zhang X*. In Vivo Identification and Induction of Articular Cartilage Stem cells by Inhibiting NF-κB Signaling in osteoarthritis. Stem Cells. 2015 Oct;33(10):3125-37. doi: 10.1002/stem.2124. Epub 2015 Aug 25. (IF=5.845) |
| 9. |
Shi Y#, Fu Y#, Tong W, Geng Y, Lui P, Tang T, Zhang X*, Dai K*. Uniaxial mechanical tension promoted osteogenic differentiation of rat tendon-derived stem cells (rTDSCs) via the Wnt5a-RhoA pathway. J Cellular Biochemistry. 2012 Oct; 113(10):3133-42. doi: 10.1002/jcb.24190. (IF=4.48) |
| 10. |
Xiang S#, Su J#, Tong H, Yang F, Tong W, Yuan W, Wu F, Wang C, Jin T, Dai K, Zhang X*. Biscarbamate cross-linked low molecular weight PEI for delivering IL-1 receptor antagonist gene to synoviocytes for arthritis therapy. Biomaterial. 2012 Sep; 33(27):6520-32. Epub 2012 Jun 12. (IF=15.304) |
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