O&T, CUHK

Academic Profile

Prof XU Jiankun, Jerry

Prof ZHANG Ning

Dr LIN Sien

Dr CHUI Chun-sing, Elvis

Dr TONG Wenxue

Dr CHEN Xiaona

Dr HSUEH Yu-sheng, Delon

CONTACT INFORMATION

Office : (852) 3505-3308

Email : jiankunxu@cuhk.edu.hk

ACADEMIC ENGAGEMENT

Postgraduate teaching:
MPhil/PhD in Orthopaedics & Traumatology

ORCID: 0000-0003-0280-9930

Professor XU Jiankun, Jerry 許建坤

Bachelor of Clinical Medicine (SUMC), Master of Orthopaedics (SUMC), PhD (CUHK)

Assistant Professor
助理教授

BIOGRAPHY

As an assistant Professor in ORT and deputy director of Areas of Excellence Centre for Musculoskeletal Degeneration and Regeneration, Dr. Xu mainly focuses on the development of innovative biomaterials for improving tendon, bone, and cartilage regeneration. With clinical training background in Orthopaedics and in-depth understanding on musculoskeletal disorders, Dr. Xu has published over 100 peer-reviewed SCI articles (total impact factor > 600, accumulative citations > 5000, H-index 38) in regenerative medicine. His representative works include original publications in Nature Medicine (2016), Advanced Materials (2024, 2025), Materials Today (2023, 2022), Advanced Functional Materials (2023), Biomaterials (2021, 2022, 2024, 2025), Journal of Clinical Investigation (2024), Nature Communications (2021), and ACS Central Science (2019).

Above efforts have earned Dr. Xu numerous academic awards, including Webster Jee young investigator, Savio L.Y. Woo young researcher, research excellence award (Faculty of Medicine, 2022), postgraduate research output award from CUHK, and Tigris education fund. As principal investigator, Dr. Xu has been supported by the General Research Fund (GRF), National Natural Science Foundation of China (NSFC, Young Scholar Scheme), Health & Medical Research Fund, Direct Grant from CUHK, and other regional grants. In addition, Professor Xu has founded two start-ups (Targene Biotech and Mag Med Biotech), aiming to push forward clinical applications of the self-developed products, with supports from Innovation and Technology Commission of Hong Kong.

Dr. Xu is life-time member of ICMRS and founding member of Sports Medicine Physician Union in Guangdong-Hong Kong-Macao Greater Bay Area. He also actively supports peer-review and serves as reviewers for many international journals.

EXPERTISE

Fracture Fixations and Evaluations
Stem Cell Characterizations and Therapies
Musculoskeletal Tissue Engineering

SPECIALISED RESEARCH AREAS

R&D of Biodegradable Implants for Orthopaedic Applications
Pathologies of Challenging Musculoskeletal Disorders
Nerve-Vessel-Bone Cross-talks
Mechanosensitive Factors in Bone, Tendon, and Tendon-Bone Insertions

SELECTED PUBLICATION

1.	JX Guo, H Yao, L Chang, WY Zhu, YT Zhang, X Li, BG Yang, BY Dai, X Chen, L Lei, ZY Chen, Y Li, LZ Zheng, WY Liu, WX Tong, YX Su, L Qin#, JK Xu#. Magnesium nanocomposite hydrogel reverses the pathologies to enhance mandible regeneration. Advanced Materials, 37 (2): 2312920 (2025).* (IF: 28.9, JCR Q1)
2.	YW Zhu, BY Dai, SA Zhang, J Liu, SX Xu, WY Liu, X Chen, HZ Zhang, Q Li, FOS Pang, WG Li, CY Wen, L Qin#, JK Xu(#co-corresponding), T Ngai#. Tissue mimetic membranes for healing augmentation of tendon–bone interface in rotator cuff repair. Advanced Materials, 37 (10): 2407358 (2025). (IF: 28.9, JCR Q1)
3.	YM An, LZ Zheng, SA Zhang, HZ Zhang, YT Zhang, HW Shao, WX Tong, ZY Chen, H Yao, ZK Wen, SX Xu, Y Li, QY Tian, LM Cheng, W Sun, L Qin#, JK Xu#. Hydrogen activates ACOD1-itaconate pathway to ameliorate steroid-associated osteonecrosis. Biomaterials, 123428 (2025). (IF: 13.4, JCR Q1)
4.	ZY Jin, JC Chen, ZM Shan, WY Liu, ZK Wen, HW Shao, TZ Liang, ZY Chen, XS Ren, DH Tan, L Qin#, J Hu#, JK Xu#. Prevalence, risk factors, prediction of robust callus formation and accelerated fracture healing in traumatic brain injury patients: a five-year study. Journal of Orthopaedic Translation, 53, 151-160 (2025). (IF: 7.9, JCR Q1)
5.	X Li, TZ Liang, BY Dai, L Chang, Y Zhang, SW Hu, JX Guo, SX Xu, LZ Zheng, H Yao, H Lian, Y Nie, Y Li, X He, Z Yao, WX Tong, XL Wang, DHK Chow, JK Xu(#co-corresponding), L Qin#. Excess glucocorticoids inhibit murine bone turnover via modulating the immunometabolism of the skeletal microenvironment. Journal of Clinical Investigation, 134, 10 (2024). (IF: 14.4, JCR Q1)
6.	L Chang, Y Luo, WR Li, FF Liu, JX Guo, BY Dai, WX Tong, L Qin#, JL Wang#, JK Xu#. A comparative study on the effects of biodegradable high-purity magnesium screw and polymer screw for fixation in epiphyseal trabecular bone. Regenerative Biomaterials, 11, rbae095 (2024). (IF: 8.1, JCR Q1)
7.	NY Zheng, JK Xu (equal-first), YC Ruan, L Chang, XL Wang, H Yao, JL Wang, R Zhang, QY Xue, N Tang, TY Ong, J Schilcher, RJ O'Keefe, L Qin. Magnesium facilitates the healing of atypical femoral fractures: A single-cell transcriptomic study. Materials Today 52, 43-62 (2022). (IF: 25.3, JCR Q1)
8.	P Zhao, J Guo, T Jiang, X Xu, S Chen, Z Li, JK Xu (co-corresponding), G Li#, L Bian#. Vacuolated coacervate mediates the bimodal release kinetics of diverse macromolecular drugs in vivo. Materials Today (2023).* (IF: 25.3, JCR Q1)
9.	JK Xu, P Hu, X Zhang, J Chen, J Wang, J Zhang, Z Chen, MK Yu, YW Chung, Y Wang, X Zhang, Y Zhang, N Zheng, H Yao, J Yue, HC Chan, L Qin, YC Ruan. Magnesium implantation or supplementation ameliorates bone disorder in CFTR-mutant mice through an ATF4-dependent Wnt/beta-catenin signaling. Bioactive Materials 8, 95-108 (2022). (IF: 20.5, JCR Q1)
10.	YF Zhang, JK Xu (equal-first), YC Ruan, MK Yu, M O'Laughlin, H Wise, D Chen, L Tian, D Shi, JL Wang, SH Chen, JQ Feng, DH Chow, X Xie, L Zheng, L Huang, S Huang, K Leung, N Lu, L Zhao, H Li, D Zhao, X Guo, K Chan, F Witte, HC Chan, YF Zheng, L Qin. Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats. Nature Medicine 22, 1160-1169 (2016). (IF: 62.4, JCR Q1)